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TSG Hoffenheim crest
Hoffenheim
Europa League
19:00
UTC, Thursday 22 October 2026
Lyon crest
Lyon

Hoffenheim vs Lyon: preview, line-ups and kick-off time

TSG Hoffenheim host Lyon at PreZero Arena on Thursday 22 October 2026, kick-off 19:00 UTC, in the Europa League (round 3). Prediction markets make Hoffenheim the favourite at 49%, with the draw at 23% (Polymarket). Hoffenheim have had 4 days of rest since playing Gladbach (Bundesliga); Lyon have had 4 after facing Nice and travel about 485 km. Hoffenheim are without 3 players (Nathan De Cat, Albian Hajdari, Patrick Wimmer); Lyon are missing 4 (Pavel Šulc, Nicolás Tagliafico, Mohamed Ouédraogo and others). Halil Umut Meler is the referee, averaging 4.4 yellow cards a game against a league average of 4.7. The forecast at kick-off is 10°C with rain.

Win chances

Hoffenheim 49%Draw 23%Lyon 28%

From Polymarket prediction market prices. For information only: Ninety has no betting links. How win chances work.

Predicted line-ups

Predicted elevens. Official team sheets usually arrive about an hour before kick-off. About predicted line-ups.

Hoffenheim 4-2-3-1

Coach: Christian Ilzer

  1. 1 Oliver Baumann GK
  2. 34 Vladimír Coufal DEF
  3. 2 Robin Hranác DEF
  4. 28 Koki Machida DEF
  5. 39 Mats Rots DEF
  6. 7 Leon Avdullahu MID
  7. 22 Alexander Prass FWD
  8. 20 Bambasé Conté MID
  9. 11 Fisnik Asllani FWD
  10. 10 Adam Hložek FWD
  11. 19 Tim Lemperle FWD

Bench

  • 37 Luca Philipp GK
  • 5 Ozan Kabak DEF
  • 47 Valentin Lässig DEF
  • 27 Andrej Kramarić MID
  • 32 Cajetan Lenz MID
  • 15 Valentin Gendrey MID
  • 18 Wouter Burger MID
  • 14 Adam Daghim FWD
  • 9 Max Moerstedt FWD

Lyon 4-2-3-1

Coach: Paulo Fonseca

  1. 40 Rémy Descamps GK
  2. 13 Zachary Athekame DEF
  3. 22 Clinton Mata DEF
  4. 19 Moussa Niakhaté DEF
  5. 16 Abner DEF
  6. 6 Tanner Tessmann MID
  7. 2 Mads Bidstrup MID
  8. 26 Kaïl Boudache FWD
  9. 99 Noah Nartey MID
  10. 24 Julien Duranville FWD
  11. 10 Pavel Šulc FWD

Bench

  • 1 Dominik Greif GK
  • 20 Felix Bacher DEF
  • 21 Ruben Kluivert DEF
  • 8 Corentin Tolisso MID
  • 18 Khalis Merah MID
  • 23 Tyler Morton MID
  • 7 Ernest Nuamah FWD
  • 11 Keito Nakamura FWD
  • 45 Rémi Himbert FWD

Injuries and suspensions

Hoffenheim

  • Nathan De Cat injury, back Late November 2026
  • Albian Hajdari injury, back A few weeks
  • Patrick Wimmer injury, back Mid November 2026

Lyon

  • Pavel Šulc injury, back About a week
  • Nicolás Tagliafico injury, back A few weeks
  • Mohamed Ouédraogo injury, back Late June 2027
  • Loïs Openda injury, back Mid November 2026
Previous meetings
  • Thursday 7 November 2024: TSG Hoffenheim 2-2 Lyon
  • Wednesday 7 November 2018: Lyon 2-2 TSG Hoffenheim
  • Tuesday 23 October 2018: TSG Hoffenheim 3-3 Lyon